9,682 research outputs found

    Canine Serology as Adjunct to Human Lyme Disease Surveillance

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    Surf zone currents and influence on surfability

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    Surfing headlands are shallow and exposed coastal features that provide a specific form of breaking wave allowing a board-rider to ride on the unbroken wave face. The seabed shape and refraction of the waves in relation to depth contours provide the greatest influence on the quality of the surf break. The large scale and orientation of the Raglan headland allows only the low frequency swells to refract around the headland to create seven different surfing breaks. Each represents a compartmentalization of the shoreline along the headland. This creates variability in wave and current characteristics depending on the orientation and bathymetry at different locations. This provides not only potential access points through the surf-zone (ie: smaller currents), but greater surfability in a range of conditions that is not possible on small scale headlands. Headlands with surfing waves can be classified as mis-aligned sections of the coast, where the higher oblique angle of the breaking surf generates strong wave-driven currents. These currents are far greater than that found on coastlines in equilibrium with the dominant swell direction, where comparatively insignificant longshore drift is found. The strength and direction of wave-driven currents in the surf zone can influence the surfability of a break. At a surfing headland strong currents flowing downdrift along the shoreline make it difficult for a paddling surfer to get to the "take-off" location of the break, or maintain position in the line-up. In comparison currents flowing updrift along headlands makes getting "out the back" relatively easy, although surfers can be taken out to sea past the "take-off" point by a fast flowing current. Field experiments at Raglan, on the west coast of New Zealand have been conducted to measure current speed and direction during a large swell event. Observations of surfers attempting to paddle through the breaking-wave zone, confirms the strength of the wave-driven currents with surfers being swept rapidly down the headland. Results from the experiments at Raglan, have shown strong currents in the inshore breaking wave zone with burst-averaged velocities attaining 0.8 ms-1, and maximum bed orbital velocities of up to 2.0 ms-1. Interestingly, further offshore the currents have been found to flow in a re-circulating gyre back up the headland. Comparisons are made from observations of waves and currents found at other surfing headlands around the world. The effect that strong currents may have on the surfability of artificial surfing reefs needs to be considered in the design process, if the surfing amenity is to be maximised for large surf conditions

    CJD mimics and chameleons

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    Rapidly progressive dementia mimicking Creutzfeldt-Jakob disease (CJD) is a relatively rare presentation but a rewarding one to become familiar with, as the potential diagnoses range from the universally fatal to the completely reversible. Patients require urgent decisions about assessment and investigation and have quickly evolving needs for treatments and support, through symptom management and end-of-life care in most cases. We have based this pragmatic review on the experiences of a specialist prion referral centre in the UK, which, unsurprisingly, is strongly biased towards seeing patients with CJD. Cases eventually proven not to have prion disease might be described as 'CJD-mimics'; being referred from UK neurologists, these are the most challenging cases. CJD in its classical presentation is very rarely mimicked; however, it is highly heterogeneous, and atypical forms can mimic virtually all common neurodegenerative syndromes. Warning features of a mimic include generalised seizures, hyponatraemia, fever, a facial movement disorder, a normal neurological examination and a modestly rapid presentation. Contrast-enhancing lesions or MRI signal hyperintensity outside the striatum, thalamus or cortex and a cerebrospinal fluid pleocytosis are key investigation pointers to a CJD mimic

    Developmental mechanisms influencing decision-making

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    The main aim of this thesis was to investigate decision making from a broad developmental perspective to clarify the role of the underlying mechanisms influencing it. Problem solving and cognitive inhibitory capacity were chartered initially through the use of hypothetical vignettes depicting socially relevant situations and through the use of the Stroop task, to tap into automatic inhibitory capacity. Initial assumptions that prefrontal cortical refinement would denote enhanced social problem ability were not confirmed. Experience emerged as distinct factor in problem solving/decision-making, with the youngest participants equally as effective in producing solutions to situations that they had the most experience in. A shift in development is observed with maturation denoting greater experience and this being applied directly to problem solving and decision-making situations. Education was identified as a possible contributory factor in decision-making and this was explored in a cross-cultural study that tapped into a non-schooled population. The results reinforced the centrality of experience in shaping decision-making. Decision-making in regards to the use of experience was then looked at through real life decision-making situations, where adolescents were asked to provide their knowledge or experience of situations where risk was involved. Adolescents possessed the necessary knowledge to distinguish between optimal and sub-optimal decisions in terms of the consequences that risk behaviours carried with them. However, many still chose to engage in risky behaviours. This paradox could also be explained by actual experience, with the suggestion that positive experience in a peer group was serving as a pool from which adolescents drew to make future decision-making. If risk behaviours were not experienced adversely, the likelihood of their repetition was high. Taken together the findings suggest that adolescents are well equipped with the cognitive skills to make decisions. Compared to younger children, they have more experience of a greater range of situations from which to extrapolate responses from. They also have a great deal of knowledge and information about the negative consequences associated with a range of challenging situations and risk-taking behaviours. However, when faced with decisions in the social domain, the behaviour of friends and perceptions of what other people are doing are powerful influences on adolescent decisions

    Guidelines for physical weed control research: flame weeding, weed harrowing and intra-row cultivation

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    A prerequisite for good research is the use of appropriate methodology. In order to aggregate sound research methodology, this paper presents some tentative guidelines for physical weed control research in general, and flame weeding, weed harrowing and intra-row cultivation in particular. Issues include the adjustment and use of mechanical weeders and other equipment, the recording of impact factors that affect weeding performance, methods to assess effectiveness, the layout of treatment plots, and the conceptual models underlying the experimental designs (e.g. factorial comparison, dose response). First of all, the research aims need to be clearly defined, an appropriate experimental design produced and statistical methods chosen accordingly. Suggestions on how to do this are given. For assessments, quantitative measures would be ideal, but as they require more resources, visual classification may in some cases be more feasible. The timing of assessment affects the results and their interpretation. When describing the weeds and crops, one should list the crops and the most abundantly present weed species involved, giving their density and growth stages at the time of treatment. The location of the experimental field, soil type, soil moisture and amount of fertilization should be given, as well as weather conditions at the time of treatment. The researcher should describe the weed control equipment and adjustments accurately, preferably according to the prevailing practice within the discipline. Things to record are e.g. gas pressure, burner properties, burner cover dimensions and LPG consumption in flame weeding; speed, angle of tines, number of passes and direction in weed harrowing. The authors hope this paper will increase comparability among experiments, help less experienced scientists to prevent mistakes and essential omissions, and foster the advance of knowledge on non-chemical weed management

    The Born-Oppenheimer Approach to the Matter-Gravity System and Unitarity

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    The Born-Oppenheimer approach to the matter-gravity system is illustrated and the unitary evolution for matter, in the absence of phenomena such as tunnelling or other instabilities, verified. The Born-Oppenheimer approach to the matter-gravity system is illustrated in a simple minisuperspace model and the corrections to quantum field theory on a semiclassical background exhibited. Within such a context the unitary evolution for matter, in the absence of phenomena such as tunnelling or other instabilities, is verified and compared with the results of other approaches. Lastly the simplifications associated with the use of adiabatic invariants to obtain the solution of the explicitly time dependent evolution equation for matter are evidenced.Comment: Latex, 12 pages. Revised version as accepted for publication by Class. and Quant. Grav. Some points explained and misprints correcte

    An Analog VLSI Model of Adaptation in the Vestibulo-Ocular Reflex

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    The vestibulo-ocular reflex (VOR) is the primary mechanism that controls the compensatory eye movements that stabilize retinal images during rapid head motion. The primary pathways of this system are feed-forward, with inputs from the semicircular canals and outputs to the oculomotor system. Since visual feedback is not used directly in the VOR computation, the system must exploit motor learning to perform correctly. Lisberger(1988) has proposed a model for adapting the VOR gain using image-slip information from the retina. We have designed and tested analog very large-scale integrated (VLSI) circuitry that implements a simplified version of Lisberger's adaptive VOR model

    A Two-Dimensional Visual Tracking Array

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    The density and concurrency available in VLSI make it an excellent technology for implementing visual image-processing. By incorporating phototransistors and analog processing elements onto a single die, the large signal bandwidths required for real-time computations can be achieved. This paper describes a VLSI chip that computes the "center of intensity" of a two-dimensional visual field. One application for this network is the localization of a bright spot of light against a dark background. Theoretical and experimental results are presented to describe the operation of the system and its suitability as a input device for tracking servo systems

    Representação gráfica de dados de experimentos de consorciação com dois níveis de variação do erro.

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    Este trabalho analisa dados de experimentos em consorciação de culturas quando a amostra aleatória vem de uma população bivariada. O objetivo é representar e interpretar informações obtidas de dois níveis de variação do erro, como, por exemplo, em experimentos usando parcelas subdivididas. É desenvolvido um método para calcular uma transformação linear para o caso em que ocorram duas correlações residuais (parcelas principais e subparcelas)

    Vaginal-rectal colonization with group A streptococci in late pregnancy.

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    OBJECTIVE: To determine the vaginal-rectal colonization rate with group A streptococci in late pregnancy. METHODS: All patients delivering at a northern New England hospital over a 38 month period had 35-37 week vaginal-rectal swabs cultured for group A and group B streptococci, using selective media and slide agglutination. RESULTS: Six thousand nine hundred forty-four screening cultures were obtained. Among these 1,393 were positive for group B streptococci and 2 for group A streptococci, yielding colonization rates of 20.1% and 0.03%, respectively. CONCLUSIONS: Vaginal-rectal colonization with group A streptococci is rare, arguing against the need for establishing group A streptococcal screening programs in pregnancy. An approach for managing this uncommon finding is presented
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